Question 1

What are Ceramides and how do they benefit us?

Accepted Answer

Ceramides are essential lipids (sphingolipids) naturally present in our skin cells, comprising approximately 50% of the stratum corneum, the outermost layer of the epidermis. Ceramides are critical for maintaining the skin barrier, protecting against UV rays, pollutants, allergens, and bacterial invasion. Ceramides also support the proper functioning of skin cells.

Question 2

What happens when we don’t have enough Ceramides?

Accepted Answer

Ceramides are crucial for moisture retention. As we age, ceramide levels decrease, leading to dry skin, weakened barrier function, inflammation, blemishes, wrinkles, breakouts, and sensitivity. Studies show that by age 30, about 40% of ceramides naturally produced by our body are lost, and by age 40, nearly 60% are depleted. Fortunately, ceramides can be replenished via skincare products such as creams, lotions, serums, and supplements. Our company was the first in the world to develop an orally consumable human-compatible ceramide supplement, which supports ceramide regeneration from within the body.

Question 3

How many types of ceramides are there?

Accepted Answer

There are over 300 molecular species of ceramides in human skin, structurally classified into 12 main groups, such as NP, AP, and EOS. More than 20 types of natural human-compatible ceramides are especially well-matched with human skin, playing vital roles in barrier function and moisture retention.

Ceramides are lipids and are categorized into short-chain and long-chain types. Short-chain ceramides are often synthetic and less effective, whereas long-chain ceramides are natural and superior in reinforcing the skin barrier and providing moisture.

Long-chain ceramides penetrate deep into the skin's lipid layers, filling in "gaps" and strengthening the barrier where there are ceramide depletion and supporting natural ceramide production.

Question 4

Can ceramides help with anti-aging?

Accepted Answer

Yes, absolutely. Ceramides reinforce the skin barrier and retain moisture, making them essential for anti-aging care. Anti-aging effects include
restoring skin barrier function, suppressing inflammation, aiding in UV damage repair, supporting epidermal stem cell maintenance and differentiation, and activating dermal fibroblasts which are cells responsible for generating connective tissues and allows the skin to recover from injury.

Restoring skin barrier function, suppressing inflammation, aiding in UV damage repair, supporting epidermal stem cell maintenance and differentiation, and activating dermal fibroblasts, cells responsible for generating connective tissues and allowing the skin to recover from injury.

Question 5

How can we fix our sensitive, dry or irritated skin?

Accepted Answer

If you have sensitive, dry or troublesome skin, you should

1) Moisturize with ceramide-based skincare (preferably human-type C24): Use natural types such as NP, AP, or EOS, and consider nano-ceramides. Combine with petrolatum or squalane to prevent transepidermal water loss.

2) Change cleansing habits: Use mild cleansers, avoid over-washing, and skip double cleansing if unnecessary. Avoid hot water and harsh rubbing.

3) Choose low-irritation formulas: Avoid alcohol, fragrance, artificial colorants, and strong surfactants. Use patch-tested products for sensitive skin.

4) Maintain daily UV protection: Use non-chemical sunscreens with physical filters and complement with hats, sunglasses, and umbrellas.

5) Care from the inside: Consume oral human-compatible ceramides or sphingomyelin supplements. Include antioxidants (vitamin C, polyphenols) and anti-inflammatory nutrients like omega-3s in your diet.

Question 6

What is the difference between short-chain and long-chain ceramides?

Accepted Answer

The difference lies in the fatty acid chain length. Short-chain ceramides have less than carbon 16 (C16) chains, while long-chain ceramides have carbon 20-26+ (C20-26+) chains. Long-chain ceramides match human skin composition and form strong barrier layers for moisture retention. Short-chain types are often synthetic and easier to formulate into cosmetics but are less effective.

Our company focuses on ultra-long-chain ceramides (C24+) and extract them from natural sources for superior skin compatibility.

Question 7

Why is carbon 24 ceramides special?

Accepted Answer

C24 ceramides are highly compatible with human skin and contribute not only to protection but also to cellular repair and troubled-skin recovery. They form the core of the skin's lipid architecture, especially for barrier and hydration function.

Among natural human-compatible ceramides, those with C24 fatty acids (e.g., Ceramide AP-C24) are particularly beneficial. We are actively researching this in collaboration with Japanese universities and medical institutions.

Question 8

Are there scientific breakthroughs related to carbon 24 ceramides?

Accepted Answer

Yes. We recently studied microRNA (miRNA) regulation involving C24-bound sphingolipids and glycosphingolipids. The findings suggest that the brain can detect skin abnormalities and signal ceramides to initiate repair.

This discovery may have implications for cell differentiation, immune response, tumor suppression, and cancer regulation.

Question 9

Can ceramides prevent skin cancer?

Accepted Answer

There is no direct evidence that ceramides prevent skin cancer. Ceramides are not sunscreens and do not block UV or destroy cancer cells. However, ceramides may indirectly help prevent skin damage by strengthening the skin barrier and reducing inflammation.

Question 10

How can we help through Indiegogo?

Accepted Answer

We are preparing to launch skincare and supplement products featuring C24 long-chain ceramides to the global market. Through your donations and support on Indiegogo, we aim to accelerate both product development and research.

Supporters will receive early access to C24 ceramide-based products, and we invite everyone to join us in spreading awareness of the importance of ceramides for troubled skin.

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